Tay-Sachs disease, the more common of the two disorders ... intensive hospital care as symptoms worsen, and our current treatment options are severely limited. But now, there's hope." ...

In one particular variant of this disease known as mucopolysaccharidosis I (MPS I), a deficiency of the enzyme alpha-L-iduronidase causes a build up of GAGs in tissues and organs, which in turn ...

Tay-Sachs disease is a rare hereditary disorder that occurs when the body lacks an enzyme that can break down fatty ...