This manuscript describes the identification and characterization of 12 specific phosphomimetic mutations in the recombinant full-length human tau protein that trigger tau to form fibrils. This ...
The revised criteria offer guidance for clinicians to determine when amyloid and tau PET are recommended. Criteria were divided into 17 common clinical scenarios with three subcategories of ...
In hippocampi from mild AD brains (center), they make more of each, and these proteins occur together (arrows; overlay yellow). In advanced AD (right), ICP27 and p-tau are abundant and co-localized.