Lipids act as extracellular and intracellular messengers to control cell fate in normal ... This occurs through signalling via the Toll-like receptor TLR4 and through endoplasmic reticulum stress ...
Our recent study links autophagy to innate immunity toll-like receptor 4 (TLR4). Further, it defines the signaling pathway downstream from TLR4 via TRIF/RIP1/p38MAPK. This pathway maintains cell ...
The lipid nanoparticles that caused an immune response interacted with the cell membrane without disrupting its signaling ...