Mediator is a common target of DNA-binding transcription factors (TFs) and also interacts with various Pre-Initiation Complex (PIC) factors. The PIC consists of TFIIA, TFIIB, TFIID, TFIIE, TFIIF, ...

据新华社报道，瑞典卡罗琳医学院10月7日宣布，美国科学家维克托·安布罗斯和加里·鲁夫坎因发现微小核糖核酸（简称微RNA）及其在转录后基因调控 ...

Biological processes are precisely regulated by TFs, miRNAs and other regulators. We aim to combine data from different sources, e.g, TF binding data (ChIP-seq and ChIP-chip), gene expression data ...

A new study has explored the RNA-binding mechanisms of the antiviral protein TRIM25. TRIM25 (green, left) finds its way to the same locations in the cell where a virus (red, middle) replicates.

TRIM25 is a protein that is important in the innate immune response against RNA viruses, such as influenza viruses, coronaviruses, or Zika virus. New research has shown how TRIM25 binds to viral ...

This work presents a valuable finding on how the interplay between transcription factors SOX2 and OCT4 establishes the pluripotency network in early mouse embryos. Despite the high quality of the data ...

NanoBRET™ 技术是最新型的BRET技术，可实现在活细胞内实时监测蛋白相互作用。 使用NanoBRET技术进行蛋白相互作用研究，通过网页或微信下载NanoBRET分享模板，提供使用心得或数据，即可获得价值200元礼品; 并有机会被邀请成为Promega特约技术讲师，参加Promega举办的 ...

There are 12 members of the SR protein family. This family of RNA-binding proteins is most known for RNA splicing. SRSF1 oversees the splicing of more than 1,500 different messenger RNA transcripts.