When naive T cells encounter antigen-presenting cells (APCs), membrane and cytoplasmic molecules rearrange at the T cell–APC contact area to form the immune synapse. Finetti et al. now reveal an ...
A key element of the T synapse is the specific relationship between the ring of integrin adhesion molecules and the central cluster of TCRs 3. (The location of adhesion molecules in the B cell ...
Wang et al, Computational immune synapse analysis reveals T-cell interactions in distinct tumor microenvironments, Communications Biology (2024). DOI: 10.1038/s42003-024-06902-2 ...
A new analysis technique The team developed a method dubbed Computational Immune Synapse Analysis (CISA ... Focusing on the immune system's T cells, the researchers showed that CISA could be ...
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