A key element of the T synapse is the specific relationship between the ring of integrin adhesion molecules and the central cluster of TCRs 3. (The location of adhesion molecules in the B cell ...

We show here active clustering of TCR–MHC molecules at the immune synapse after interaction between aAPC and T cells. This multivalent system allows identification and stimulation of antigen ...

Wang et al, Computational immune synapse analysis reveals T-cell interactions in distinct tumor microenvironments, Communications Biology (2024). DOI: 10.1038/s42003-024-06902-2 ...