These receptors allow T cells to sense and ... which supports lymphoid structure formation. T cell activation is a process that requires extra nutrients, which could be difficult to source from ...

A new cell therapy targeting CD7 on leukaemia cells gives a potentially effective treatment for patients with T-cell acute ...

CAR T-cell therapy is a type of immunotherapy. CAR stands for chimeric antigen receptor. You might also hear it called a type of adoptive cell transfer. CAR T-cell therapy is a very complex and ...

B-cell activating factor receptor chimeric antigen receptor (CAR) T-cell therapy caused cytotoxic effects on all chronic lymphocytic leukemia (CLL) cell lines. “We hypothesized that BAFF-R CAR T ...

The α-latrotoxin, which is dangerous for humans, causes severe muscle contractions and spasms. Scientists from the University ...

A new study by Rice University researchers led by Jason Hafner could open new pathways for understanding how cholesterol ...

Antigen-presenting cells (APC) are important in antigen presentation to naïve T cells. Receptors on the cell surface discriminate molecules as "self" or "foreign" (Delves & Roitt, 2000).

Moreover, Dr. Adusumilli was gathering funds to start an innovative new mesothelioma clinical trial testing a new form of immunotherapy called chimeric antigen receptor (CAR) T cell therapy. “I’m a ...

The first step of toxin activity is the recognition of a specific receptor on the target cell surface. When bound to the receptor, toxins can act at the cell membrane by interfering with signal ...

In an article published in the journal Science Advances, they now describe the circumstances under which the CD95 receptor—which is responsible for cell death—reacts. In biological cells ...

a technique that allows imaging of a thin layer of frozen proteins or cells using electrons. While studying the structure of the 5-HT3A receptor, Dr. Introini found that some molecules consisted ...