Findings from these systems indicate that chemokines have indirect effects on T cell differentiation through effects on APC trafficking or cytokine secretion, as well as direct effects through ...

Another critical aspect of applying encapsulation to sorting cytokine-secreting cells is the ability to recover the cells in a viable and functionally normal state. Thus, PBMC were encapsulated ...

The following is a summary of "Impact of HBsAg reduction via siRNA treatment on natural and vaccine (BRII-179)-induced ...

1,2 (2) Engineered CAR T cells expressing therapeutic payloads can transform the immunosuppressive environment of solid tumors, such as through producing and secreting proinflammatory cytokines. 3,4 ...

The study analyzed both immunological (receptor activation, cytokine secretion, T-cell modulation) and metabolic parameters (metabolic state) in dendritic cells—specific immune cells—derived ...

IN8bio (INAB) unveiled INB-600, its next generation gammadelta T cell-based TCE platform. It is designed to address one of the biggest ...

In CAR-T cell therapy, clinicians obtain T cell source material directly from a patient (autologous), or from a donor (allogeneic), modify them, and re-introduce them to the patient. Working with ...

CAR-T cell therapy is currently used successfully ... it results in lower pro-inflammatory cytokine secretion." Ferreira noted that the team also made sure to run tests on both naive Tregs and ...

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Proprietary platform represents the first known approach capable of sustained γδ T cell expansion, eliminating target cells with robust potency; INB-619, a next generation γδ ...