It had previously been noted that there was a correlation between the number of spacers in CRISPR loci and resistance to phage infection, and this led to the suggestion that CRISPR loci might be ...
The CRISPR locus is transcribed and processed to generate mature CRISPR RNAs, each encoding a unique spacer sequence. Each crRNA associates with Cas effector proteins that use crRNAs as guides to ...
Then, if the virus is encountered again, that sequence produces a guide ... "We were interested in how fast this CRISPR system changes its spacers, specifically in the gut microbiome, to better ...
However, CRISPR has also been adapted to do other things too, such as turning genes on or off without altering their sequence. There were ways to edit the genomes of some plants and animals before ...