Such studies would employ a dense map of single-nucleotide polymorphisms (SNPs) to detect association between a marker and disease based on LD between the marker and a disease-risk gene variant.
A single nucleotide polymorphism, or SNP, is a single base-pair difference in the DNA sequence of individual members of a species; not necessarily a pathological mutation, but commonly studied as ...
To avoid confusion, single nucleotide polymorphisms (SNPs) are not usually referred to as mutations, which is a term generally reserved for p53 sequence changes that arise during tumorigenesis or ...
The application of pharmacogenetics in identifying single nucleotide polymorphisms (SNPs) in DNA sequences that cause clinically significant alterations in drug-metabolizing enzyme activities is ...
Epigenome-wide association studies in neurodevelopmental disorders Takeo Kubota, Kunio Miyake and Takae Hirasawa Part III. Single Nucleotide Polymorphisms, Copy Number Variants, Haplotypes and eQTLs: ...