In 5 patients severe metabolic acidosis (serum pH less than 7.0 in 3) was associated with a near normal pH in the cerebrospinal fluid and with normal mental function.
Arterial blood gas revealed pH 7.36, pCO 2 26 mm Hg, and bicarbonate 14.5 mmol/L, reflecting a severe metabolic acidosis with respiratory compensation. Fasting insulin and glucose levels were normal.
Kidney failure in turn leads to azotemia; depending on the severity and duration of renal dysfunction, metabolic acidosis, hyperkalemia, and abnormal fluid balance may also develop, leading to ...
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