Background: Since the introduction of sentinel lymph node biopsy (SLNB), its use as a standard of care for patients with clinically node-negative cutaneous melanoma remains controversial.

sentinel lymph node biopsy (SLNB) is an accurate method to stage the nodal basin. Interim outcomes data from MSLT-I showed no differences in 5-year melanoma-specific overall survival between the ...

If you have a diagnosis, your doctor may need to find out if cancer cells have spread, though they won’t do this for melanoma in situ. The first step is to perform a sentinel node biopsy.