Aldosterone is a steroid hormone that plays a critical role in the homeostasis of sodium, potassium and volume. Aldosterone is secreted primarily by cells of the zona glomerulosa in the adrenal ...

Aldosterone antagonists already have a significant role for patients with severe HF, and there is benefit in the setting of LV dysfunction following MI. The adjunctive therapy for HF with one or ...

highly selective aldosterone synthase inhibitor, to change the current treatment paradigm. In addition, the event will include an overview of the ongoing Advance-HTN and Launch-HTN pivotal trials ...

Developed by Boehringer, BI 690517 is a selective aldosterone synthase inhibitor (ASi). Boehringer Ingelheim Human Pharma head Carinne Brouillon said: “These encouraging Phase II data not only ...