We used patient iPSC-derived retinal pigment epithelium (RPE) and retinal organoids for a common RP2 nonsense mutation that causes X-linked retinitis pigmentosa, to test if translational read ...

The macula is made up of rods and cones that sense light and behind those are a layer of nourishing cells called the retinal pigment epithelium. When this support layer fails, it causes macular ...

To overcome the challenge, the team used AI and a humanoid for biological experiments to identify the ideal conditions for creating retinal pigment epithelium cells, which supply nutrients to ...

This accumulation eventually leads to the breakdown of the retinal layer called the retina pigment epithelium. It also disrupts blood vessels that are situated behind the retina. This disrupts ...

The California Institute for Regenerative Medicine (CIRM), the state's stem cell agency, has awarded a two-year, $6 million ...

This research evaluates the effects of various gene therapy viral vectors on RPE cells to determine efficacy for therapeutic ...