Overview of RNA repair – There is an emerging appreciation of the existence of “RNA repair” pathways that rely on RNA ligases to maintain or manipulate RNA structure in response to purposeful RNA ...

Our cells need to be able to recognize potential invaders as a threat, the key function of the body's innate immune system.

The BiaB advantages over traditional methods of RNA manufacturing, include high throughput of high-quality pharmaceutical ...

Mitochondrial DNA (mtDNA)-encoded RNA molecules undergo extensive processing to generate mature RNA, including removal of ...

Alternative pathways of RNA processing are regulated in response to signaling cues often coordinating expression of gene networks in response to physiological change including in development and ...

A research team from the University of Barcelona's Institute of Neurosciences described a novel molecular mechanism that modifies protein synthesis and impacts RNA processing in Alzheimer's ...

This target centers on RNA regulation, which, when disrupted in humans, is often linked to neurodegenerative diseases like Alzheimer's disease and Parkinson's disease, as well as many types of cancer.

Understanding RNA Processing Kinetoplastids have helped scientists understand RNA processing events, such as RNA editing. To date, gene expression resulting from RNA editing has been described in ...

These findings not only advance our understanding of spliceosome function but also open potential opportunities to target RNA processing for therapeutic interventions in diseases associated with ...

Researchers at the University of Toronto have shown that an important class of DNA-binding factors can also bind to RNA, regulating gene expression through various mechanisms. The study ...

We study minor spliceosome which is a parallel pre-mRNA splicing machinery in the cells of most metazoan organisms. Our main aim is to investigate mechanism and regulation of this nuclear machinery, ...