RNA breaks destined for repair are inflicted by sequence-specific or structure-specific endoribonucleases during physiological RNA processing (e.g. tRNA splicing; kinetoplast mRNA editing) and under ...

Alternative pathways of RNA processing are regulated in response to signaling cues often coordinating expression of gene networks in response to physiological change including in development and ...

Results of a multinational genetic study suggest that defects in transfer RNA (tRNA) processing may be responsible for many cases of the neurodegenerative disease pontocerebellar hypoplasia (PCH).

We study minor spliceosome which is a parallel pre-mRNA splicing machinery in the cells of most metazoan organisms. Our main aim is to investigate mechanism and regulation of this nuclear machinery, ...

Our laboratory carried out research in two areas. In one, we studied the structure and mechanism of activity of the catalytic RNA moiety of the RNA processing enzyme ribo-nuclease P (Rnase P). In the ...

Mitochondrial DNA (mtDNA)-encoded RNA molecules undergo extensive processing to generate mature RNA, including removal of ...

The BiaB advantages over traditional methods of RNA manufacturing, include high throughput of high-quality pharmaceutical ...

While we’ve mapped the RNA-binding sites for a number of C2H2 zinc finger proteins, we’re just starting to scratch the surface of investigating their functions.” ...

For investors interested in scheduling a one-on-one meeting with the Remix management team, please contact your Evercore representative. About Remix Therapeutics Remix Therapeutics is a clinical-stage ...

Researchers from The University of Texas at Austin discovered important information about an enzyme that can protect cells ...