The loss of function of these two factors induced GnRH deficiency that could be reversed by pulsatile administration of exogenous GnRH. “The demonstration that the gonadotropin deficiency in ...
Gonadotropin-releasing hormone (GnRH) and its analogues have been extensively used in clinical medicine since they were identified and synthesized in 1971. Native GnRH stimulates gonadotrophs of ...
It is thought that the same hypothalamic pulse generator may both trigger the pulsatile release of GnRH and LH and also cause hot flashes. Thus, if melatonin suppressed this pulse generator in ...