SFA Therapeutics, Inc., a clinical-stage biopharmaceutical company developing novel oral small-molecule biosynthetic ...

This fuels the excessive immune response typical of psoriasis. Targeted interruption of the inflammatory cycle With the key role of SSAT in the inflammatory process, the researchers have ...

Discover recent findings that indicate that c-Rel expression is upregulated in psoriatic skin lesions and decreases following treatment.

Identify the most appropriate psoriasis mouse model(s) to test efficacy of pathway-specific drugs identified by the AMC, and generate and provide mice to the CRP for preclinical testing and evaluation ...

A potential new psoriasis treatment restores the function of certain anti-inflammatory immune cells in a targeted manner.

In a mouse model with psoriasis-like skin inflammation, it was shown that inhibiting SSAT can restore the regulatory function of Treg cells and break the cycle of inflammation. Thus, the ...

A protein called NF-kB c-Rel has been found to intensify the symptoms of psoriasis, offering a potential new target for ...

"Psoriasis can be a challenging condition to manage due to long-term treatments with various side effects. SFA-002's effect in the imiquimod-induced mouse model is compelling. The results ...