Past efforts to develop CoV vaccines have used whole-inactivated virus, live-attenuated virus, recombinant protein subunit, or genetic approaches. CoV spike (S) proteins mediate cellular ...
HHMI scientists and their colleagues discover a new mechanism of protein synthesis. Ribosomes are the cell’s molecular machines, responsible for translating genetic information in messenger RNA into ...
A subunit vaccine makes use of just a small portion of a pathogen. For a virus, the vaccine can contain just a piece of the protein coat that surrounds the virus's DNA (or RNA). Even small portion ...
MPA-CF 3 specifically binds to COPZ1, a subunit of COPI. Upon binding, MPA-CF 3 destabilizes COPZ1 and disrupts the interaction of COPZ1 with the EV-A71 2C protein in a concentration-dependent manner.
Avidity Biosciences Inc. has announced two new precision cardiology development candidates targeting rare genetic cardiomyopathies. AOC-1086 targets phospholamban (PLN) cardiomyopathy and AOC-1072 ...