They can also appear spontaneously during the replication of DNA. Mutations generally fall into two types: point mutations and chromosomal aberrations. In point mutations, one base pair is changed.

Researchers developed a new gene-editing strategy that dramatically boosts the effectiveness of gene therapies in the liver, a breakthrough that could lead to new treatments for about 700 genetic ...

Scientists from the Cancer Dependency Map (DepMap) at the Broad Institute of MIT and Harvard and Columbia University have ...

We used a novel geometric hyperbranched RCA (HRCA) reaction to detect point mutations in small amounts of human genomic DNA in solution. Furthermore, linear RCA, using pre-formed circles as ...

However, changes in the genome do occur. These are known as mutations. Mutations can have two results: no protein is expressed an altered protein is expressed Some mutations can affect a few bases ...

Mutations occur continuously and can be spontaneous. Most are caused by errors when the DNA is copied prior to cell division. They can also happen because of: ionising radiation close ionising ...

Researchers have discovered that about 5% of adult cancers rely on a gene called PELO to survive, offering a promising drug ...

The Rice lab of bioengineer Gang Bao and collaborators at Baylor College of Medicine have developed a new gene-editing strategy that dramatically boosts the effectiveness of gene therapies in the ...