It is known and used worldwide by leading research groups and many of the world’s largest pharmaceutical companies. This conditionally immortalised human podocyte cell line was originally developed by ...

In this study, we have demonstrated, using two independent normal podocyte cell lines, a previously unsuspected aspect of human podocyte biology: that differentiated podocytes are insulin ...

These conditions include diabetic nephropathy, membranous nephropathy and FSGS. We therefore use our GEnC and podocyte cell lines to understand how they contribute to the filtration barrier in health, ...

Podocytes were insulin and serum starved for 2 24 h before stimulation. Unless stated otherwise, 220 nmol/l insulin was used. Cells were stimulated for 15 min with insulin. Total RNA from ...

Cells expressing PAX8 (nucleus, red) considered podocyte precursors, line the outer Bowman’s capsule. Activated during the low salt-fasting mimicking diet (LS-FMD), the cells migrate and trans ...

Cells expressing PAX8 (nucleus, red) considered podocyte precursors, line the outer Bowman’s capsule. Activated during the low salt-fasting mimicking diet (LS-FMD), the cells migrate and trans ...