A scaleable method for the liquid-phase separation of plasmid DNA from RNA. In the course of experiments on the potential of nucleic acid compaction for enhancement of chromatographic adsorption ...

A plasmid is a small, circular, double-stranded DNA molecule that is distinct from a cell's chromosomal DNA. Plasmids naturally exist in bacterial cells, and they also occur in some eukaryotes.

The current cost for DNA synthesis is less than $0.1 per nucleotide pair. In step 2, the gene fragment is integrated into a circular piece of DNA, called a plasmid, which is the main delivery vehicle ...

The Gene Vector Core was awarded the Blue Flame Award. The award is given to scientists who have at least one plasmid deposited that has been distributed at least 100 times. The Gene Vector Core was ...

CRISPR-based gene-editing tools are being developed to correct specific defective sections of the genome to cure inherited genetic diseases, with some applications already in clinical trials. However, ...