Peyer's patches as immune hubs: Peyer’s patches in the small intestine are crucial for inducing T-cells in response to dietary antigens, forming a first line of defense against tumor formation .
While IgAN manifests through problems in the kidneys, the disease is believed to originate in the small intestine. Specialized lymphoid tissue in the ileum, called Peyer’s patches, act as sites ...
When protein antigens are injected into the small intestine of wild-type mice, they are passed to dendritic cells in the Peyer's patches; similar experiments in M-cell-deficient mice result in ...