Portal hypertension is an abnormal increase in blood pressure defined clinically as hepatic venous pressure gradient 5 mmHg in the hepatic portal vein system. Causes of portal hypertension ...

By contrast, a fuller understanding of the pathophysiology of portal hypertension and variceal hemorrhage has occurred only over the past three decades. This has led to significant advances in ...

Cirrhosis was therefore eliminated as a diagnosis. Of all the causes of portal hypertension, extrahepatic portal vein obstruction is the most likely to manifest with massive splenomegaly.