[1] The purpose of this discussion focused on the pathophysiology of sepsis is to provide the neonatal care provider with information, now widely accepted on the pathophysiology of sepsis in ...

Despite treatment, morbidity and mortality from neonatal sepsis remain high ... An expanded understanding of the complex pathophysiology of sepsis in infants may lead to novel therapeutic ...

Reduced parenteral glucose during neonatal infection redirects hepatic metabolism to oxidative phosphorylation and gluconeogenesis, dampens systemic proinflammatory responses, and significantly ...

In the pathophysiology and therapy of neonatal sepsis, consideration of these time changes and the balance of ROS and antioxidants with concomitant changes in inflammatory cytokines would appear ...

Neonatal sepsis is a major cause of morbidity and mortality in preterm infants. Clinical diagnosis is difficult and no reliable diagnostic test exists. Interleukin-6 (IL-6) is a central mediator ...

Left ventricular outflow tract obstruction is the most prevalent but under-recognised structural heart defect leading to ...