The pathogenesis of protein contact dermatitis is unclear but may involve a type I (immunoglobulin E [IgE], immediate) hypersensitivity reaction, type IV (cell-mediated delayed) hypersensitivity ...

contributing to the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies. Name: Microtubule-associated protein tau Target Synonym: MAPT, MTBT1, Paired helical ...

There is a potential link between Alzheimer's disease and the herpes simplex virus-1 (HSV-1), which is a common cause for ...

Figure 5: Age-dependent increase in insoluble tau in P301L (JNPL3) mouse brains. We have reported a transgenic mouse line, JNPL3, expressing human tau with the P301L mutation that develops NFT ...

A comprehensive toolkit for spatial biology Orr’s team follows protein expression across ... It's another step towards understanding tau pathogenesis and cellular senescence, and their links ...

Currently, there is ongoing discussion on the precise mechanism of AD pathogenesis ... the β-amyloid waterfall theory, and the Tau protein theory. The majority of patients diagnosed with ...

Past studies found that patients diagnosed with AD, as well as some other neurodegenerative disorders, exhibit an abnormal accumulation of tau protein in their neurons. Tau protein is a ...

Hyperphosphorylation of the tau protein can result in the self-assembly of intraneuronal tangles of tau filaments, which are involved in the pathogenesis of PSP and CBD. The chromosomal region ...

Important subside pour mieux comprendre la maladie d'Alzheimer. Aurélien Lathuilière, a neurologist at the HUG Memory Centre and research associate in the Departments of Cell Ph ...