Opioids also block pain signals and have sedative effects ... some patients who used opioids showed an improvement in leg symptoms and sleep, with one case of physical dependence on the drug ...
Symptoms include leg pain, numbness, and slow-healing sores. Management involves lifestyle changes, medication, and in severe cases, surgery like bypass grafts or angioplasty. Smoking cessation ...
While some symptoms such as chest pressure, aching, or squeezing are well-known, one less recognised sign is leg pain. This can manifest as a "gripping" or "cramping" sensation in the legs ...