What are the side effects of continuous use of painkillers? Which medications should not be taken without a doctor's advice?

NSAIDs-- or nonsteroidal anti-inflammatory drugs -- are among the most common pain relief medicines in the world. Every day more than 30 million Americans use them to soothe headaches, sprains ...

Medications, including over-the-counter (OTC) and prescription drugs, are available to manage pain and provide relief.

[7] Where paracetamol or topical NSAIDs are ineffective for pain relief, NICE suggests consideration of an oral non-selective NSAID or a COX-2 inhibitor, prescribed with a proton pump inhibitor (PPI).

Arthritis Care Research News Alerts. 2008;59(2):227-233. Nonsteroidal anti-inflammatory drugs (NSAIDs) are used to treat arthritis, which affects one-third of all adults. These drugs are available ...

Previously accessible without prescription in the UK, diclofenac became a prescription-only ... to gastrointestinal bleeding ...

There are dozens of medications available with or without a prescription to treat ... These topical drugs can help provide pain relief for people with arthritis that is in just a few joints ...