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腾讯网
11 天
韩国回顾性分析揭示PIK3CA基因突变在原发灶与转移灶间具有高度一致性
一项韩国回顾性分析揭示PIK3CA基因突变在原发灶与转移灶间总体一致率达87.8%。 乳腺癌作为全球女性中最常见的恶性肿瘤 [1] ,其早期诊断与治疗对 ...
BioWorld
3 天
GSC-002639 shows antitumor efficacy against PIK3CA-mutant tumors
Mutations in the PIK3CA gene are present in about 4% to 36% of cancers such as breast, ovarian, endometrial and colorectal cancer, among others.
Nature
26 天
FDA approves PI3Kα inhibitor that does double duty as a degrader
The FDA has approved Genentech’s inavolisib (Itovebi) in combination with the CDK4/6 inhibitor palbociclib and the oestrogen-receptor antagonist fulvestrant for endocrine-resistant, PIK3CA ...
SurvivorNet on MSN
2 个月
For Advanced Breast Cancer With a PIK3CA Mutation, A New Three-Drug Combination Doubles ...
New research indicates that a drug called Inavolisib is effective at treating a type of metastatic breast cancer with a ...
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