Growth, bone density, histology and fracture number are important outcome parameters, but are not simple to measure accurately and reproducibly in children with severe OI. For example, using ...

Osteogenesis imperfecta (OI), also known as brittle bone disease, is a rare genetic disease affecting the connective tissue and bones. In this disease, bones become extremely fragile and break or ...

Osteogenesis imperfecta (OI) is an inherited (genetic) bone disorder that is present at birth. It is also known as brittle bone disease. A child born with OI may have soft bones that break ...

Osteogenesis imperfecta (OI) means “imperfectly formed bone”. Brittle bone disease is a genetic condition, which means it is present from birth, and can potentially be passed on from parents ...

"In addition, the fact that all the patients with OI type V have the same IFITM5 mutation could prove to be an advantage for ...