Some recent studies have provided examples of NK cell involvement in allograft tolerance. NK cells possess allele-specific inhibitory receptors that could interact with specific alleles of HLA and ...

By connecting with its tumor-associated overexpression ligands, such as MICA, MICB, and ULBPs, NKG2D, an activating NK cell receptor can modulate the cytotoxic capability of NK cells against ...

Clinical relevance: Receptor engineering has significantly advanced NK cell-based cancer immunotherapies. As technical hurdles are overcome, these innovative treatments are poised to revolutionize ...

Researchers from Naya Biosciences Inc. and collaborators presented preclinical data on NY-303, a natural killer (NK) cell engager bispecific antibody targeting both GPC3 and NKp46. NKp46 is a cell ...

They also proposed a new immunotherapy strategy based on receptor antagonism. Their study was published in Nature Immunology ...

Phase 1 Basket Study for B Cell-mediated Autoimmune Diseases to Assess FT522 as Add-on to Standard-of-care Induction and ...

Fate Therapeutics (FATE) presented initial clinical and translational data from the company’s Phase 1 study of FT522 in relapsed / refractory ...