New research published in Cancer Cell suggests that tumour-associated neutrophils can have antitumorigenic ('N1') or protumorigenic ('N2') functions, a plasticity that has been well described for ...

Nearly 150 years ago, scientists discovered that specialized blood cells serve a vital role in immune system protection ...

The question of putative mechanisms of action continues to haunt psychopharmacology. Put simply, we know these drugs work, but we have very little idea how. We make guesses based on the ...

The term idiopathic neutropenia describes a benign disorder of granulopoiesis characterized by the unexplained reduction in the absolute neutrophil ... pathogenetic mechanisms: first, the primary ...

Using blood progenitor cell lines that can be induced to undergo maturation towards fully functional neutrophils, we are elucidating the molecular mechanisms that control neutrophil differentiation ...

The study is a valuable addition to the field, showing how particulate matter may be acting via nociceptor neurons towards neutrophilic asthma exacerbations. The solid evidence for the role of a ...

The mechanism for this process is thought to involve ... and chemotaxis into the arterial wall. The dual action of MIF, both on chemokine expression and as a ligand for chemokine receptors ...

Such efforts have even been shown to lower humanitarian costs by as much as 30 percent, providing an average savings of US$2.8 for every US$1 invested. The Famine Action Mechanism (FAM) is a global ...

Adults with infections usually rely on emergency myelopoeisis, a rapid-response mechanism of hematopoietic stem cells that generates large numbers of immune cells, including neutrophils.

Owning one of the best action cameras is crucial if you want to capture your daring exploits. After all, you probably can't take your $2,500 mirrorless camera diving with sharks, and I doubt many ...

The manuscript explores how bacterial evolution in the presence of lytic phages modulates b-lactams resistance and virulence properties in methicillin-resistant Staphylococcus aureus (MRSA). The work ...

Sublingual (SL) formulation of ‘1104 achieved comparable responses to subcutaneous (SQ) and intravenous (IV) injections‘1104 SC and SL dosing ...