Nearly 150 years ago, scientists discovered that specialized blood cells serve a vital role in immune system protection ...

New research published in Cancer Cell suggests that tumour-associated neutrophils can have antitumorigenic ('N1') or protumorigenic ('N2') functions, a plasticity that has been well described for ...

The question of putative mechanisms of action continues to haunt psychopharmacology. Put simply, we know these drugs work, but we have very little idea how. We make guesses based on the ...

The term idiopathic neutropenia describes a benign disorder ... disease entities on the basis of the underlying pathogenetic mechanisms: first, the primary autoimmune neutropenia mediated by ...

Neutropenia in individuals with a congenital ... act on C/EBPs to induce G-CSF and G-CSFR transcription. This proposed mechanism was supported by the findings that sirtuin 1 co-precipitated ...

Using blood progenitor cell lines that can be induced to undergo maturation towards fully functional neutrophils, we are elucidating the molecular mechanisms that control neutrophil differentiation ...

The study is a valuable addition to the field, showing how particulate matter may be acting via nociceptor neurons towards neutrophilic asthma exacerbations. The solid evidence for the role of a ...

Such efforts have even been shown to lower humanitarian costs by as much as 30 percent, providing an average savings of US$2.8 for every US$1 invested. The Famine Action Mechanism (FAM) is a global ...

Adults with infections usually rely on emergency myelopoeisis, a rapid-response mechanism of hematopoietic stem cells that generates large numbers of immune cells, including neutrophils.

The chronic and progressive inflammatory disease bronchiectasis is characterised by permanent bronchi dilation and by ...

The manuscript explores how bacterial evolution in the presence of lytic phages modulates b-lactams resistance and virulence properties in methicillin-resistant Staphylococcus aureus (MRSA). The work ...

In a report released today, Andrew Fein from H.C. Wainwright maintained a Buy rating on Wave Life Sciences (WVE – Research Report), with ...