Researchers have identified a natural substance, hederagenin, that blocks the NPFFR1 receptor, a protein involved in pain perception in the brain and spinal cord.
This is not an impartial review. Having long been a convert to the view that the neuropeptide oxytocin is of great importance in social and reproductive behavior and emotions, I am sympathetic to ...
Using this strategy, I have matched two orphan GPCRs with their ligands–GPR107 with the neuropeptide neuronostatin, and GPR146 with the connecting peptide, or C-peptide, of pro-insulin. My overall ...
The best characterized pathways are the orexigenic neuropeptide Y/Agouti-related protein and the anorexigenic pro-opiomelanocortin/cocaine- and amphetamine-related transcript neurons in the ...