IL-2 and IL-15, which have a crucial role in the development and proliferation of NK cells, are also potent inducers of cytotoxicity ... dependent and cytokine mediated and are relayed through ...

Acute Myeloid Leukemia (AML) remains one of the most challenging hematological malignancies to treat, with relapse and ...

The TIMING™ platform, supported by AI, enables advanced label-free cell analysis for cancer immunotherapy. By observing ...

Following the discovery of inhibitory KIR and the understanding that they play a role in preventing NK cell killing of self MHC I-expressing tumor cells, investigators began to research the ...

Findings provide a foundation for further exploration of natural killer cells for the development of future treatments and therapies for a range of lung diseases, including chronic obstructive ...

SEM image of the membrane protrusions of normal and intratumoral NK cells. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by ...

To mediate antibody-dependent cellular cytotoxicity (ADCC), NK cells ... immunotherapy is enhancing therapeutic mAb-mediated CD16 activation of NK cells. CAR-NK cells containing multi-specific ...

antibody-mediated cytotoxicity. B cells play a critical role in skin allograft rejection by promoting the differentiation, expansion and survival of donor-specific memory T cells. NK cells ...

Creating cancer therapies based around natural killer cells could offer similar levels of efficacy to CAR-T therapies, but at around one hundredth of the cost. Researchers at MD Anderson Cancer ...

Previous studies have suggested that austocystin D is oxidized by cytochrome P450 (CYP) oxygenases which then induces DNA ...

During this process, the CD28-mediated co-stimulatory signal plays a central role ... IL-7, IL-15, IL-21, etc. 2. Enhance NK cell proliferation and cytotoxicity Studies have shown a significant ...