Aldosterone antagonists, such as spironolactone or potassium canrenoate, are the preferred first-line diuretics in the management of patients with cirrhosis and ascites, because aldosterone is the ...

Purpose: The clinical benefits, adverse effects, pharmacokinetics, and recommendations for the appropriate use of the aldosterone antagonists spironolactone and eplerenone in patients with heart ...

Aldosterone is a steroid hormone that plays a critical role in the homeostasis of sodium, potassium and volume. Aldosterone is secreted primarily by cells of the zona glomerulosa in the adrenal ...