Upon binding GFP, one nanobody, aptly named Enhancer, yielded a fourfold fluorescence increase, to a level comparable to that of eGFP alone. Structural analysis revealed that in the GFP-Enhancer ...

Due to the ease of nanobody engineering, they can be employed in three nanobody-based therapeutic platforms: platform A, receptor antagonists to interfere with or block the activation of a certain ...