Figure 1: My 1967 thesis drawing of an excitable membrane showing three separate types of ion channels Na, K and leak (L), as well as the Na-K ATPase pump, a "carrier," a serine protease modeled ...

A subset of arthritis patients suffer from neuropathic pain arising from damage to joint nerves. Some of the main targets of these injured nerves are the voltage gated sodium channels NaV1.7 and ...