Directly after re-exposure to these cues, AMPA receptor subunits GluR2 and GluR3 and NMDA receptor subtype 2B were downregulated in synaptic membranes of the medial prefrontal cortex, and clathrin ...

Pathologically high levels of extracellular glutamate can cause excitotoxicity, when postsynaptic receptors such as NMDA and AMPA are overactivated, allowing high levels of calcium influx that trigger ...

The group focuses on studying the mechanisms guiding activity-dependent development of glutamatergic circuitry in the limbic system and in particular, the roles of ionotropic glutamate receptors in ...