The patients with myotonic dystrophy consisted of ... and was thought to have manifestations of both myotonia congenita and muscular dystrophy. The group of patients with nonmyotonic dystrophy ...

The increased muscle tone of myotonic muscular dystrophy is described as myotonia, and it manifests ... It has been described as congenital onset, juvenile onset, and adult onset, based on the ...

In recent years, a growing understanding of myotonic dystrophy type 1 (DM1)—an often ... restored muscle force and reduced electrophysiological myotonia. Target engagement was detected in ...

The gene that causes myotonia congenita is recessive. This means if myotonic goats reproduce with other types of goats that don’t have this condition, their offspring won’t have it either.

Clinical examination of the child’s mother, who exhibited abnormal facies, revealed grip myotonia during handshake. This strengthened the suspicion of congenital myotonic dystrophy type 1 (DM1 ...

The disease can lead patients to experience early cataracts, myotonia, muscle weakness ... is under development for congenital myotonic dystrophy (CDM) and potential use in other CNS ...