No biological system has been studied by more diverse approaches than the actin-based molecular motor myosin. Biophysics, biochemistry, physiology, classical genetics and molecular genetics have ...

The interaction of myosin and actin proteins is at the core of our current understanding of sarcomere shortening. How does this shortening happen? It has something to do with a sliding interaction ...

Muscle fibers in children with SMA type 1 show substantial differences in components of the myosin protein called heavy ...

Numerous motor and structural proteins compose a highly ordered structure known as the sarcomere, the basic unit of muscle contraction in heart and skeletal muscles. Sarcomeric myosin heavy chain ...

We’ve already mentioned hemoglobin, a protein that transports oxygen via the blood, and ferritin, an iron carrier. Many of us have also heard of actin and myosin, proteins that assist in building ...

The family of Type II sarcomeric myosin genes encodes essential motor proteins that drive contraction in striated muscle. Mutations in almost all 10 members of the gene family have been associated ...

The researchers validated the model's predictions against experimental and simulation data across several systems, achieving consistent results and even uncovering a novel allosteric regulation ...

Dairy cows are heavily dependent upon their skeletal muscle tissue as they go through their production cycles.