Demyelination is the condition in which preexisting myelin sheaths are damaged and subsequently lost, and it is one of the leading causes of neurological disease (Figure 2). Primary demyelination ...

the fatty sheath that covers nerve cells in the brain and spinal cord. Chronic loss of the protective myelin harms neurons.

Discover various promising treatments in development to address the unmet needs of people with Charcot–Marie–Tooth disease.

Inhibiting TLR7, an immune signaling protein, may help preserve the protective layer surrounding nerve fibers in the brain ...

Those disruptions are due to inflammation and damage to the myelin sheath, the protective covering around nerve fibers, and they produce a wide range of symptoms. While there is no cure for MS ...

MS is neurodegenerative because the damaged myelin sheath and oligodendrocytes (cells that produce myelin) delay communication between nerve cells, thus resulting in the inefficient functioning of ...

Inhibition of an ESI1 target promotes oligodendrocyte myelin production in mice ... and to manage aging-related nerve sheath deterioration, according to study led by experts at Cincinnati Children ...

A research team at Case Western Reserve University is pioneering a novel approach to MS treatment by targeting toxic ...