This belief found early support through the observation that, as in humans, the major histocompatibility complex (MHC) of the NOD mouse (designated H2 g7) contributed the main component of ...

One model relies on the transgenic expression of human molecules such as HLA (human MHC) molecules or immunoglobulins in immunocompetent mice. HLA-transgenic mice are used to identify antigens ...

An intracellular sensor that tracks the quality of so-called MHC-I molecules which aid the immune system in identifying and ...