Scientists recreate mouse from gene older than animal life New research sheds light on evolutionary origins of stem cells with groundbreaking experiment to create mouse using ancient genetic tools ...
The nanoparticles led to gene edits in 30% of the brain stem cells in the mouse model. "Transfecting 30% of the whole brain, especially the stem cells, is a big deal. These cells migrate and ...
The 2012 Nobel prize to Shinya Yamanaka demonstrated that it is possible to obtain stem cells from "differentiated" cells just by expressing four factors, including a Sox (Sox2) and a POU (Oct4) gene ...
However, mimicking the human brain in a mouse is difficult; adding human genes for APOE4 to mice ... Microglia depletion reduces human neuronal APOE4-related pathologies in a chimeric Alzheimer's ...