A research team has identified subtypes of astrocytes in the white matter of the mouse brain, one of which possesses an ...

"The fact that we could alter mouse behavior by selectively manipulating an astrocyte ensemble poses an intriguing question: are astrocytes a substrate for memory? We plan to further investigate ...

Their screen identified histone deacetylase 3 (HDAC3) inhibitors that suppressed neurotoxic astrocyte reactivity in culture and in vivo, and protected nerve cells from degeneration in three separate ...

“It always seemed like the brain is defending itself and it’s fighting the tumor, but now we know the astrocytes aren’t actually helping.” The researchers first implanted mouse glioblastoma cells in ...

When faced with chronic stress, why do some people develop anxiety and depressive symptoms while others show resilience? A protein that acts as a cannabinoid receptor and is present in the structure ...

The mechanisms of pathological astrocyte responses during multiple sclerosis remain unclear. Kadowaki et al. found in MS mouse models that CLEC16A suppresses astrocyte pathogenic activities ...

Erythropoietin-producing hepatoma (Eph) receptors, including EphA4, are expressed on the cell surface and involved in brain development, which involves extensive pruning of synapses. A variant in ...

A research team has identified different subtypes of white matter (WM) astrocytes, including a unique type with the ability to multiply and potentially aid in brain repair. Using single-cell RNA ...

Mice resilient to stress had more CB1 receptors in the BBB than mice with depressive-like behavior or mice not exposed to stress.