Mayo Clinic researchers found that a gene variant, the TPMT∗8 allele, is associated with reduced metabolism of the thiopurine class of drugs. TPMT∗8 is relatively common in individuals of African or ...

This is because AFLP fragments represent unique restriction sites that are either present or absent in each individual and thus only one allele ... Sequencing is becoming an important tool for ...

Mayo Clinic researchers found that a gene variant, the TPMT∗8 allele, is associated with reduced metabolism of the thiopurine class of drugs. TPMT∗8 is relatively common in individuals of African or ...

Current molecular analysis is delivered mostly as multiple single tests at relatively high cost. Technology is changing and the introduction of next-generation sequencing (massively parallel ...

Mayo Clinic researchers found that a gene variant, the TPMT∗8 allele, is associated with reduced metabolism of the thiopurine ...

Explore a cfDNA library preparation workflow that provides high yield and conversion to improve sensitivity and detection of low variant allele frequencies (VAF). Cell-free DNA (cfDNA) contains ...