Given the crucial role of insulin resistance in the pathogenesis of T2DM, understanding the molecular mechanism of insulin resistance is vital for the development of new therapies. Although ...
Our data point to a mechanism in which Acrp30 enhances insulin action, resulting in decreased hepatic glucose output and decreased serum glucose levels. Importantly, we performed all the mouse ...
insulin action, or both. The chronic hyperglycemia of diabetes is associated with long-term damage, dysfunction, and failure of various organs, especially the eyes, kidneys, nerves, heart ...