Mitochondria organelles came from primordial bacterial endosymbionts and still preserve distinct genes for important functions like making ATP. To speed the emerging therapeutic research into the ...

Immunotherapy, which uses programmed immune cells to selectively destroy cancer cells, has transformed cancer treatment.

But mitochondrial transfer has faced skepticism—in part because no one really knew why it works. "We assumed it was ...

The immune system plays a key role in detecting and destroying cancer cells. Cancer immunotherapy works by programming immune ...

Mitochondrial transfer was studied using mitochondrial-specific fluorescent reporters and multiple in vitro and in vivo models. Tumor-infiltrating lymphocyte functions, metabolic profiles ...

Researchers have identified the transfer of mitochondria with mutated DNA from cancer cells to immune cells as a key ...

To speed the emerging therapeutic research into the transfer of mitochondria between cells, 31 researchers have developed consensus recommendations for common terminology that describes ...

An emerging area of research is the evolutionarily conserved transfer of mitochondria between cells. Yet researchers have lacked unique and universally accepted terms and practices to describe such ...

Now, researchers have identified the transfer of mitochondria with mutated DNA from cancer cells to immune cells as a key mechanism of immune evasion and resistance to immunotherapy. Targeting ...