However, this study provides a valuable foundation for defining the cell biology and therapeutic potential of neuron–microglia interactions in both health and disease. Neurodegeneration has long ...

thus damaging vulnerable neuron types. These effects range from the acceleration of neurodegeneration caused by mutant SOD1 acting in astrocytes and microglia to the direct production of ...

By mapping OPC activity in unprecedented detail, researchers are paving the way to better understand the brain’s adaptive ...

An illustration of how a microglia cell (gray) wraps around a pyramidal neuron (PyN – green and blue) and chandelier cell synaptic endings (ChC, red) to help synapses grow on the axon initial ...

Researchers at Indiana University School of Medicine are examining the brains of individuals with asymptomatic Alzheimer's ...

More information: Hannah Scheiblich et al, Microglia rescue neurons from aggregate-induced neuronal dysfunction and death ...

Weill Cornell Medicine investigators have found that two genetic variants that confer high risk of Alzheimer's disease (AD) ...

Dozens of rodents have been generated that model various aspects of ALS, like motor impairment or degeneration of motor neurons. No model recapitulates the human disease perfectly. By organizing ...

Investigators have found that two genetic variants that confer high risk of Alzheimer's disease (AD) together trigger a harmful inflammatory response in the brain's immune cells, particularly in ...

Scientists have recently completed the most ambitious effort yet to construct such a map: a complete document of every neuron and every connection in the brain of an adult fruit fly. The research ...

An edited version of that discussion follows. In your book, you talk about the "Jennifer Aniston neuron" and what that experiment taught us about memory. Schwartz: The Jennifer Aniston neuron ...

The world's population is aging, and dementia and Alzheimer's are becoming more common. Alzheimer's also tends to impact more ...