DNA methylation is a crucial epigenetic modification that plays a significant role in gene regulation in bacteria. This process involves the addition of a methyl group to specific DNA sequences ...

Not all genes are active at all times. DNA methylation is one of several epigenetic mechanisms that cells use to control gene expression. This straightforward experiment demonstrated that it was ...

Variably methylated regions (VMRs) were found to predict gene expression better than promoter regions. In NSC lineage ...

Colorectal cancer is typically diagnosed after age 50, but in recent years the disease has been increasingly found in younger ...

This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...

This process is carried out by the enzyme RNA polymerase, which binds to the promoter region of the gene and synthesizes the mRNA. Epigenetics is the study of heritable changes in gene expression that ...

It has been established that hypermethylation of promoter regions in specific ... potentially mitigate these effects by maintaining DNA methylation levels and preventing chromosomal instability.